A simple, efficient, precise and accurate spectroscopic method has been developed and validated for quantitative estimation of sertaconazole nitrate in bulk and tablet dosage form. Sertaconazole nitrate standard solution was scanned in the UV rang (400-200 nm) in a 1 cm quartz cell in a double beam UV spectrophotometer. The max of sertaconazole nitrate was 260 nm. The method obeys beers law in the concentration range from 10-70 μg/ml. The correlation coefficient was found to be 0.9989 and regression of the curve was found y = 0.0116x - 0.0805 with excellent recovery 99-101%. Limit of detection and limit of quantitation were found to be 0.503928964 mg/ml and 1.527057468 mg/ml respectively. The method was validated for several parameters like accuracy, precision as per ICH guidelines. Value of % RSD and % recovery was found satisfactory, hence the proposed method is precise, accurate and economical hence can be used for routine analysis.
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